Terbutaline is a medication used to delay preterm labor. Terbutaline should not be used to stop or prevent premature labor in pregnant women especially in women who are not in a hospital.

Fda Warns Against Terbutaline For The Treatment Of Preterm Labor

Terbutaline injection is sometimes used to stop or prevent premature labor in pregnant women however it is not approved by the Food and Drug Administration for this purpose.

Terbutaline for preterm labor. Doses of 5 to 10 mg PO every 4 to 6 hours until 37 weeks gestation have been studied in clinical trials. Continuous terbutaline infusion in 8 women with premature labour arrested the uterine contractions within 15 h in 7 of them when an infusion rate of 10 microgramsmin was used. It is in a class of drugs called betamimetics which help prevent and slow contractions of the uterus.

The plasma concentrations of terbutaline were in the range 10-14 microgramsL after 1 h. However Terbutaline has not been efficacious across the board and studies of the drug in injectable oral and even continuous infusion have shown no efficacy. Oral terbutaline should not be used for prevention or any treatment of preterm labor because efficacy has not been established and safety concerns similar to IV administration exist Death and.

An Overview of Terbutaline and Premature Labor Terbutaline sulfate Brethine is a prescription medication used to treat asthma and emphysema. This drug crosses the placenta. Infusions of terbutaline 25 mcgmin in women in premature labor has caused decreases in serum potassium of up to 16 to 2 mEqL.

Terbutaline Pregnancy Warnings Animal studies show that rat offspring exhibit alterations in behavior and brain development including decreased cellular proliferation and differentiation when this drug was administered subcutaneously during the late stage of pregnancy and lactation period. This medicine may increase risk of heart problems and other serious side effects when given to a pregnant woman for a long time. It could cause serious side effects in pregnant women such.

The FDA approved terbutaline in 1974. The drug is sometimes used off-label an unapproved use for. Using this medicine to prevent or treat preterm labor can harm pregnant women.

Terbutaline also is used for delaying premature labor by relaxing the muscles of the uterus that are responsible for expelling the fetus at the time of delivery. Terbutaline a beta-adrenergic agonist is a potent cardiovascular CV stimulant that is associated with an increased risk of pulmonary edema and maternal and fetal CV abnormalities. Terbutaline has caused serious side effects including death in pregnant women who took the medication for this purpose.

Terbutaline is not approved for use by anyone younger than 12 years old. What brand names are available for terbutaline. Terbutaline is not safe to use in a pregnant woman to prevent premature labor.

It is part of a group of medications called beta adrenergic agonists. Terbutaline injection should only be given to women who are in a hospital and should not be used to treat premature labor for longer than 48 to 72 hours. Brethine Bricanyl Brethaire are no longer available in.

Terbutaline became popular for the treatment of preterm labor in the late 1990s when some cases of preterm labor appeared to respond to the drug. Terbutaline is approved to prevent and treat bronchospasm narrowing of airways associated with asthma bronchitis and emphysema. Terbutaline is used off-label to treat preterm labor also known as premature labor though it is not approved for this use.

This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects caused by the medicine. Per the FDA oral terbutaline should not be used for prevention or any treatment of preterm labor due to lack of efficacy and serious maternal cardiovascular safety concerns increased fetal heart rate and neonatal hypoglycemia. Another study in ten healthy males produced a mean decrease in serum potassium of 09 mEqL following a bolus injection of 025 mg terbutaline followed by an infusion of 5 mcgmin.

Terbutaline shouldnt be used to slow down or stop premature labor in pregnant women.